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These safety concerns may become a bigger part of legal evaluations as the use of these drugs expands

Clinical trials and post-marketing surveillance data consistently show that the following side effects occur commonly, though frequencies vary by product and dose: Nausea (affecting 15-50% of patients, depending on the specific product and dose) Vomiting and diarrhoea Constipation Abdominal pain or discomfort Reduced appetite These gastrointestinal symptoms typically diminish over time as the body adjusts to the medication, usually within 48 weeks

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If you switch to tirzepatide 7 days after your last semaglutide dose, you still have approximately 50% of your semaglutide dose circulating

Short-chain fatty acids (SCFAs) are produced primarily by the fermentation of nondigestible carbohydrates, such as dietary fiber, by the microbiota