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To confirm these predictions, we measured glucose uptake with 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose (2-NBDG) 72 in B6 MZB and FoB

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in the highest dose cohorts (up to 12 mg weekly), gastrointestinal adverse events as a composite were reported in over 50% of participants at some point during the treatment period