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The minimum BMI for semaglutide (Wegovy) under FDA labeling is 30 without any additional conditions, or 27 with at least one weight-related comorbidity such as type 2 diabetes, hypertension, or dyslipidemia

Shanmugam G, Challa AK, Litovsky SH, Devarajan A, Wang D, Jones DP, et al
The activated endothelium in cerebral microcirculation plays an essential role in neuroinflammatory processes in individuals with MetS [8]

The takeaway: even at the maximum dose, most side effects are uncomfortable but not dangerous when you arrive at that dose through proper titration

With more data, healthcare providers can make better treatment decisions and patients can be better informed about potential side effects
[37:02] Chantal, thank you so much for joining me today

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