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375 Moreover, an elevated intake of dietary salt can exacerbate autoimmune conditions by promoting the induction of pathogenic Th17 cells, contributing to MS
LOXs are nonheme iron-dependent enzymes implicated in PUFA peroxidation and ferroptosis, with arachidonate 15-lipoxygenase (ALOX15) playing a significant role [32,33,34,35]
Heterozygous carriers have an enzyme activity of about 55% of the normal mean and normal levels of glutathione [18]
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