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Remarkably, the mechanisms underlying the positive effects of GLP-1 RAs appear complementary to that of SGLT-2 inhibitors (SGLT2i), a therapeutic pillar of the treatment for both HFrEF and HFpEF, providing incremental benefits in reducing HF exacerbations and hospitalizations [45]

S.LandgrenS.MinthonL.et al

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Changes in blood pressure may occur secondary to weight loss