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In controlled laboratory settings, cadaver knees are subjected to forces that mimic real-life dynamic activities

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Dihexa's synaptogenic effects require activation of the c-Met receptor, as demonstrated by experiments using c-Met-specific short hairpin RNA (shRNA) which completely abolished Dihexa's capacity to induce spine formation

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This raises the possibility that GPX3 might protect interstitial fibrotic ECM from oxidative damage with a potential impact on the resolvability of fibrotic matrix

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