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In laboratory and pre-clinical research settings, native GLP-1 serves as the primary pharmacological reference standard for studying GLP-1 receptor binding, activation, and downstream signalling as well as the broader incretin axis and its connections to pancreatic -cell biology, appetite regulation, gastric motility, cardiovascular function, and neuroprotection

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Kittner SL, Talbott AL, Vishneski SR, Narbaiza J, Shields JS

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