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Improvement should require a coherent pattern: pathway marker change, stable renal and nutritional context, parallel improvement in imaging or function, and absence of compensatory harm in another metabolic axis
10.1161/CIRCRESAHA.121.318241 24
They can state that glutathione 'supports antioxidant activity' or 'promotes cellular health' because those are structure-function claims permitted under 21 CFR 101.93
However, tetracycline, minocycline, dapsone, and topical corticosteroids are also mentioned as treatment options (234, 235, 237)
doi:10.1002/brb3.1726 Kolovrat M, Gojkovic S, Krezic I, et al
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