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In this regard, it is interesting that IgG antibodies that show similar FcRn binding properties can have variable plasma half-lives due to differences in biophysical properties, such as pI and net charge, which affect cellular handling 83,84,85,86,87
164 Notably, larger doses or longer durations of GLP-1RA therapy have been associated with an increased risk of cholelithiasis, 165 a primary risk factor for AP
What makes it selective: unlike GHRP-6 and GHRP-2, it stimulates GH release without significantly elevating cortisol, prolactin, or appetite
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[4] Whilst these incretin-based therapies offer significant metabolic benefits, they commonly affect gastrointestinal function, including bowel movements
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