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main purpose Receptor binding and activation of signaling pathways IGF-1 LR3 activates two main downstream signaling pathways by binding to the IGF-1 receptor (IGF-1R): PI3K/Akt pathway: promotes cell survival, glucose metabolism, and protein synthesis

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basis for ophthalmic applications (PMID: 19668473) Muscle: Improved muscle regeneration following injury

Groups that should avoid or seek clinician guidance first Pregnancy and breastfeeding: GHK-Cu has not been adequately studied in pregnancy or lactation

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Environmental toxins and Parkinsons disease: putative roles of impaired electron transport chain and oxidative stress