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Rather than relying on a single receptor system, this combination activates both the GHRH and ghrelin pathways simultaneously, producing a GH pulse that is significantly larger than either peptide can achieve alone
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Insect Mol Biol
(B-D) Traces demonstrate acute effects of Ex-4c on membrane potential when the cell was pretreated with (B) 10 M linopirdine+10 M XE991, (C) 100 nM tertiapin-Q, or (D) 200 M tolbutamide
doi: 10.1210/jc.2013-3644 15 RosenstockJWyshamCFrasJPKanekoSLeeCJFernndez LandLet al
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