While gastrointestinal symptoms (nausea, vomiting, diarrhea, constipation) affect many patients initially, severe or persistent symptoms may necessitate dose adjustment, temporary dose reduction, or consideration of alternative therapies
Resistance training, in particular, has been shown to support muscle growth and metabolic health while on calorie-restricted diets
Notably, women also appear to discontinue GLP-1 therapy more frequently because of gastrointestinal adverse effects than men in some cohorts (Brchers et al., 2024)
What types of medical evaluations are conducted
Daily fluctuations of 1 to 3 pounds are normal and meaningless
doi: 10.1016/j.bioorg.2018.11.022 314 JiYZhengKLiSRenCShenYTianLet al