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Cozza G, Rossetto M, Bosello-Travain V, Maiorino M, Roveri A, Toppo S et al (2017) Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: the polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center
The final GLP-1GLP-1R complex contained 72,067 atoms, including 16,320 TIP3 water, 44 sodium, 99 chloride, 102 POPC, and 33 CHL molecules, whereas the SR18GLP-1R complex contained 79,689 atoms, including 18,915 TIP3P water, 51 sodium, 54 chloride, 102 POPC, and 33 CHL molecules
In animal studies, there were concerns about adverse effects on fetal development
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