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Acknowledgements We acknowledge support from National Institute on Alcohol Abuse and Alcoholism (AA029831), National Institute on Aging (AG057557, AG061388, AG062272, AG07664), from National Cancer Institute Case Comprehensive Cancer Center (CA221718, CA043703, CA2332216)
The exploration of GLP-1s mechanisms also present opportunities for novel therapeutic developments
Of course, most researchers do not commit to maximum doses from the start
The USA will be the largest country in the GLP-1 receptor agonist market in 2030, valued at $80,345 million
A gradual climb from the starting dose to the maximum therapeutic dose
Further elucidation of such interrelationships is also necessary for exploring the underlying mechanisms and developing novel therapeutic options
