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Simple habits such as staying hydrated, choosing fiber-rich whole foods, and swapping poorly tolerated foods can improve comfort and long-term adherence

Faster escalation means reaching the effective dose sooner but potentially dealing with more intense gastrointestinal side effects

However, the steep costs and unequal access create substantial hurdles

Adrian Heald arranged funding of the semaglutide intervention in consultation with Onagh Doyle and Chris Daly

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Some patients are able to sustain weight loss by making the healthy behaviors learned during treatment a permanent part of their lifestyle, while others may regain weight if they fail to adopt lasting changes