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The peptide upregulates MMP-2 expression in dermal fibroblasts by 85%, facilitating breakdown of damaged collagen and enabling cellular migration through dense matrix environments, while simultaneously enhancing production of tissue inhibitors of metalloproteinases (TIMPs) to prevent excessive degradation

Neither is "better" in a research sense, because the two are studied for different mechanistic questions

The typical maintenance dose is 1,000 mcg administered IM once monthly