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Germ-free mouse models show persistently lower baseline BDNF and GDNF levels, altered dendritic spine shape, and impaired synaptic plasticity, highlighting the need of microbial signals for neurotrophic homeostasis [159]

He says darker-skinned people produce more melanin, which works to limit inflammation

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Conversely, cardiac-specific overexpression of OGG1 protects mitochondrial DNA and reduces cardiac fibrosis in pressure overload models [208]

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