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GLP-1RAs can downregulate the expression of the myostatin gene in C2C12 myotubes, reversing the upregulation of atrophy factors and downregulation of myogenic factors (MyoD/G) (136)

Horm Metab Res (1995) 27(8):3725

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Ozempic and Wegovy are under-the-skin drugs, meant to be injected once a week in the stomach, thigh or arm through a pen-like instrument