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Common gastrointestinal side effects occur in many patients and include: Nausea (most common, typically improving after 4-8 weeks) Vomiting Diarrhea Constipation Abdominal pain or discomfort Decreased appetite These effects result from the drugs' mechanism of actionslowing gastric emptying and affecting gut motilityrather than indicating tissue damage or malignancy

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Patients developing signs of allergic reactions should discontinue the medication and seek immediate medical attention

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Ensure adequate hydration To increase tolerance, pair it with Vitamin C, probiotics, and fiber-rich foods