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10.3389/fcell.2016.00116 8 KaiserS
L-carnitine used to treat hyper-ammonia in children with urea-cycle enzyme deficiencies26 and valproate-induced hyper-ammonia.27 The protec tive effects of L-carnitine are centrally mediated by activation of metabotropic Glu receptors at the level of brain ammonia uptake and/or mitochondrial energy metabolism
Light therapy, such as photodynamic therapy, may also be a treatment option for some patients
This means fewer side effects like jitteriness or insomnia and more sustainable, steady weight loss
With purpose-build scoring systems being debunked as useful, and mixed diagnostic criteria being used in case studies, this makes potential novel interventions difficult to study
lvarez-Arrao V et al
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