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Standard lab handling: Requires routine peptide precautions, including aseptic technique, PPE, and controlled storage

Common reconstitutions are 5 mg + 2.0 mL (2.5 mg/mL), 10 mg + 3.0 mL (3.33 mg/mL), or 10 mg + 2.0 mL (5.0 mg/mL)

Clinical trials, including the SURMOUNT-1 study, have shown significant weight reduction in participants with obesity or overweight, even those without diabetes

The ubiquitin system

Therefore, pharmacological treatments are being increasingly considered, especially for those with NASH or significant fibrosis

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