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HIF-1 triggers long-lasting glutamate excitotoxicity via system xc- in cerebral ischaemia-reperfusion
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There was less certainty regarding the relative effects of the drugs to each other, particularly for outcomes beyond weight loss (e.g., cardiovascular outcomes), for which reason the institute judged the comparison between tirzepatide and semaglutide as promising but inconclusive (P/I)
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