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Autophagy 16 , 14821505 (2020)

They were mixed with jr PPO1-wt in a mass ratio of 1:100 in 300 mM Tris-HCl at pH 7.8

However, about 10-15% of acetaminophen is metabolized by CYP2E1 into a toxic metabolite known as NAPQI (N-acetyl-p-benzoquinone imine).[ref] Detoxification with glutathione: NAPQI then needs to be neutralized with glutathione, which is catalyzed using the GST genes