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For these reasons, a Y250-containing site is likely to be less sensitive to the impacts of hypothetical chemical modification/remodeling of the disulfide bonds mentioned
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JAMA Oncol
Sixth, peptide stability, solubility, and purity are useful laboratory characteristics, but they do not establish human safety, pharmacology, or clinical value
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The mixed inhibition mode implies that KA binding is not limited to the active site
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