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Compared with normal skin fibroblasts, a greater number of keloid fibroblasts displayed a senescent phenotype and were arrested at the G0/G1 phase using a serum-limited culture approach, indicating the senescent tendency of keloid fibroblasts under simulated ischemic stress

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Coverage, however, varies widely by plan and employer, and many insurers still place restrictions on coverage for weightloss medications

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Importantly, much of the initial weight loss comes from reduced food intake and water loss rather than pure fat lossthis is normal and expected during the first few weeks of any GLP-1 or GIP-based therapy