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Leptin, a key regulator of satiety and appetite, is decreased in active IBD, probably due to exhaustion after transient overproduction related to TNF- hyperactivity

Vitamin B6 is included to support energy metabolism and the effective utilization of amino acids, further enhancing the supplement's anabolic potential

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In experimental studies, genotoxic effects were reported for stavudine 180 , efavirenz, and tenofovir disoproxil fumarate alone and in combinations 183