Hormonal Imbalances Thyroid dysfunction, insulin resistance that predates GLP-1 therapy, low sex hormones (testosterone in men, estrogen/progesterone balance in women), and elevated inflammatory markers all influence metabolic rate and fat distribution
The glycosuria induced by these medications creates a glucose-rich urinary environment that can promote genital mycotic infections (thrush) in 1015% of patients, particularly women
[1] These effects are typically dose-dependent, most pronounced during dose escalation, and tend to diminish over time
the list goes on
Unger JW, Moss AM, Livingston JN
In addition, when GSH is depleted, monocyte-derived macrophages significantly increase their production of reactive oxygen species (ROS), further amplifying oxidative damage within the CNS ( Overall, GSH helps limit unwanted immune attacks in the brain