doi:10.1007/s10067-014-2530-5
Through downregulating monocyte chemoattractant protein-1 expression, semaglutide treatment, an FDA-approved GLP-1 RA medicine targeting Type II diabetes mellitus (T2DM) (Christou et al., 2019), inhibited monocyte migration and infiltration from the circulatory system to inflammatory regions (Pontes-da-Silva et al., 2022)
Some researchers posit that this effect occurs via an intrinsic mechanism, while others hypothesize that it may be mediated through the paracrine actions of insulin or somatostatin
Nothing urgent, but enough to make me think harder about what I was doing for my health
Safety Considerations When Combining Ashwagandha and Semaglutide No major direct pharmacokinetic interactions exist between ashwagandha and semaglutide, but several indirect effects warrant attention
This protocol was designed to optimize efficacy while maintaining an acceptable safety profile