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Oh TJ, Song Y, Jang HC, Choi SH

Some retrospective analyses suggest patients using GLP-1 medications may experience fewer RA flares or reduced inflammatory markers compared to those on other diabetes treatments

This finding supports the role of glucose toxicity in DM-related dopaminergic dysfunction and cognitive impairment, suggesting that advanced glycation end products (AGEs) and their precursor methylglyoxal (MGO) are linked to cognitive impairment and changes in the dopaminergic system

A 2021 human study published on NCBI found that GI issues were more common with semaglutide 2.4 mg compared to a placebo

I., Lundbom, J

Diabetes (2004) 53(9):2397403