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In human clinical trials, individuals ingesting ME-3 for two weeks gained a remarkable 49% increase in the ratio between reduced to oxidized glutathione

Redox state of glutathione in human plasma

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Transplantation of mSOD1 G93A microglia into PU.1 / mice, which lack macrophages, neutrophils, T- and B-lymphocytes, and microglia, did not induce motor neuron degeneration, confirming that mSOD1 in microglia alone is not sufficient to initiate disease ([17, 18, 35]

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