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Rapid weight loss can include both fat mass and lean mass unless the patient follows a structured plan

For research only

Semaglutide- and tirzepatide-class medications carry real, documented risks discussed in the safety section above

Dont take vitamin B12 supplements if you have sensitivities or allergies to vitamin B12, cobalt, and any other ingredients in the medication

Topical application does not typically cause systemic side effects

The effect was due to on-target inhibition of GPX4 rather than reduction of GSH levels, as, contrary to the marked reduction in GSH observed with L-buthionine-sulfoximine (BSO), we observed only a small reduction with SCLA2 at 10 M and no change at 1 M (Extended Data Fig