People with certain conditions, such as severe kidney disease or allergies to B12 components, should discuss suitability with their provider
Free Cu2+ is toxic (Fenton reactions, hydroxyl radicals), but the GHK-Cu complex is stable, diffusible and delivers copper in a targeted manner to copper-dependent metalloenzymes: lysyl oxidase (collagen/elastin crosslinking), Cu/Zn superoxide dismutase (SOD1, antioxidant defence), tyrosinase (controlled melanogenesis), dopamine-beta-hydroxylase
Martin, L.F., et al
Thymalin also promotes T-cell differentiation, boosting antiviral immunity, and shows potential in preventing immune suppression in severe infections like COVID-19 (9)
Heavy metals and toxic substances, including aluminium in cookware, could drastically increase the risks and effects of MTHFR and other SNPs
doi: 10.1093/rheumatology/keq108 183 AngiolilliCBaetenDLRadstakeTRReedquistKA