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IRS rules require the medication to treat a specific medical condition

A randomized, parallel-group, multicenter, phase 3 trial found that tirzepatide caused pancreatitis (5 mg n = 3, 10 mg n = 2, 15 mg n = 1) in patients with type 2 diabetes mellitus (Del Prato et al., 2021), and another double-blind, randomized, multicenter, phase 3 trial found that tirzepatide also caused pancreatitis (15 mg n = 2) in obese patients with type 2 diabetes mellitus (Garvey et al., 2023)

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[1] [2] This medication works by mimicking the natural hormone GLP-1, which stimulates insulin secretion, suppresses glucagon release, and slows gastric emptying

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10.1254/jphs.fp0061322 29 DrmicD.SamaraM.VidovicT.MalekinusicD.AntunovicM.VrdoljakB.et al (2018)