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Most patients adapt to semaglutide within 4-6 weeks, with gastrointestinal tolerability improving as the body adjusts to the medication's effects on digestion

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et al., 2018

For a family medicine and cannabis-medicine practice, that distinction is the clinical takeaway: a treatment can ease a symptom and still fall short of the rehabilitation goal that brought the patient into care, which is exactly the kind of honest gap analysis this specialty needs