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Some examples: irritability, crying, sleeping more or less than usual, withdrawn, refuses to nurse/feed, wimpers or weeps, wants to be held (or refuses to be held), sensitivity to light/pain/noise, complaining of limb pain

FDAs 2024 review summarized several early human studies and the later OPTIONS study

Current Pharmaceutical Design, 26(29), 35383554

Can Butaphosphan + Vitamin B12 Injection help in increasing muscular performance

Notes: Comfort-first positioning reduces returns

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