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Jan 21, 2026 Some researchers see dramatic improvements in body composition within weeks

Whole brains were collected and immediately frozen in liquid nitrogen

The limited role of exercise in weight loss and its greater importance in improving health, body composition, and insulin sensitivity [19:45]

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What we do in that scenario is keep patients at the lowest dose before escalating, to let their body adjust to the medication. While the low and slow method can work for many people, with side effects often leveling out over time, for some, they arent tolerable, even at the lowest starting dose

If HbA1c doesn't improve after 3 months on medication, dosing or approach may need adjustment