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The extended activity duration increases the window during which adverse effects could manifest

NICE guidance (NG28) supports their use in type 2 diabetes when glycaemic control is inadequate with other therapies

It also aligns with the observed improvements in cardiometabolic markers seen in clinical trials of incretin-based therapies

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[4] [5] Preterm infants should not receive probiotics unless specifically directed by neonatologists in controlled clinical protocols