These are open research questions, and the combination data come largely from preclinical and short-term studies that have not been validated in large human trials
Callander N, Markovina S, Eickhoff J, Hutson P, Campbell T, Hematti P, Go R, Hegeman R, Longo W, Williams E, Asimakopoulos F, Miyamoto S
Because it enhances detox enzyme activity, it may either reduce medication effectiveness or change how quickly drugs are cleared from the body
You lose the copper peptide benefit and the antioxidant benefit in one application
10.1016/j.ymthe.2020.09.024 Mol
Pros: Premium formulation Includes skin-hydrating ingredients Good absorption Cons: Expensive Limited availability 8