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Our findings indicate that inhibition of Trx2 by APR-246 can be the explanation for this effect 47

When we are young or disease-free, 10% of glutathione is in the inactive (oxidized) state, while 90% is in the active form

Peter Strouhal, a medical director at Alliance Medical Ltd in the UK and lead author of the new study, said in a statement: "We noticed unusual uptake in one of our patients on a GLP-1 agonist, which prompted a wider review across our network." He added: We found that these altered patterns are increasingly common, yet there is currently no national or international guidance in the UK addressing this emerging issue

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