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352 In the context of FHM type 2 deficient NKA not only results in the impaired K + buffering but is also linked to down-regulation of astrocytic EAAT2 glutamate transporters, which dives pathophysiology of this form of migraine
PMID: 113 WeiLChenQZhengYNanLLiaoNMoS
One literature example which catch our eyes, where deuterated drug studied is the selective replacement of hydrogen with deuterium is used to enhance metabolic stability, reduce formation of unwanted metabolites, and improve overall pharmacokinetic profiles
Exendin-4 and sitagliptin protect kidney from ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction
To view or add a comment, sign in For colleagues interested in #tuberculosis treatment and #CNS #pharmacology, Im happy to share that our manuscript, Central nervous system antituberculosis drug exposures in a rabbit model of tuberculous meningitis, has now been published in Antimicrobial Agents and Chemotherapy
Three Honest Explanations We do not yet have the randomized trial that would settle this, so Ill give you the three explanations that actually hold up, not a tidy headline
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