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Many patients report increased energy and focus within the first few days
For example, a healthy person taking a 500 mcg oral B12 supplement will only absorb about 10 mcg
Perhaps most importantly, individuals with malabsorption issues may take oral supplements faithfully yet remain deficient, wasting money and time while symptoms persist
doi.org/10.1038/nature03000 Smart, N., et al
The most practical approach for many protocols involves starting with a 5mg vial for the early escalation phases and switching to a 10mg vial once weekly doses are higher
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