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Older secretagogues like GHRP-6 and GHRP-2 also activated this pathway, but they came with significant side effects: hunger, cortisol spike, prolactin elevation

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If you are considering any of these therapies, come prepared: bring a clear symptom list, recent labs, a record of current medications and supplements, and a plan to work on the lifestyle basics in parallel

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Chittora et al., 2022

Tumour initiating cells and IGF/FGF signalling contribute to sorafenib resistance in hepatocellular carcinoma