glp-1 medications approved for type 2 diabetes 2025 Indications GLP-1/GIP RA Summary Sheet and Beyond! In the phase 3 ACHIEVE-1

The FDA has approved these medications for use in patients with type 2 diabetes and for weight loss in individuals meeting certain criteria, such as BMI and weight-related conditions

The primary resistance mechanisms include mutations in FCY2 , encoding cytosine permease (which mediates drug uptake), and mutations in FCY1 , encoding cytosine deaminase (required for 5-FC activation) (Longley et al., 2003

Try to aim for at least 8 glasses of water per day, especially before and after meals

When should I do it before every meal

To correct for 500mcg dosing, draw 0.067mL per injection, but recognize this introduces measurement error with standard insulin syringes

It helps alleviate insulin resistance as well as obesity induced by a high-fat diet