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Because signals from cancer cells can dynamically influence ECM characteristics, targeting intracellular signaling pathways represents a promising approach for ECM modulation [158]

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The type of immune suppression experienced appears to be dependant on a number of factors, including the species involved, the route of administration, the doses tested, and the methods used to detect the effects [82]

184 This editing is crucial for averting pathogenic IFN-I responses triggered by Z-RNA-dependent ZBP1 activation