Dependency on Maintenance Doses: Continuous maintenance may be required to preserve the whitening effect, adding to long-term costs
In certain pain-related conditions in mice, studies have demonstrated that the combination of Vitamin B1, B6, and B12 effectively alleviates pain, with a more potent effect compared to the use of individual vitamins alone
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However, the TCT requires a relatively expensive instrument and high cost of testing limits the outreach of the technique in developing countries [151, 152]
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