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It seems that the reason carnitine was unable to increase muscle carnitine concentration in these studies for 2 reasons: Poor bioavailability (only 20% for of a 2-6 g dose is absorbed) and Because the transport of carnitine into the muscle was limited
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Ali MH, Moghaddam B, Kirby DJ et al (2013) The role of lipid geometry in designing liposomes for the solubilisation of poorly water soluble drugs
In animal studies, MOTS-c administration has been found to increase exercise capacity and improve metabolic parameters independent of activity levels
Nutrients 16(22)
In rare cases, intramuscular B12 may cause a drop in potassium
