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GLP-1 receptors are also widely expressed in the brain [9, 10], where their agonists produce a selective release of neurotransmitters [11, 12] and increase GLP-1 receptor expression in glia after a mechanical lesion of the rat brain has been reported [38]

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Ideal candidates for the semaglutide weight loss program include individuals with a body mass index (BMI) of 30 or higher, or those with a BMI of 27 and one weight-related health condition, like high blood pressure or type 2 diabetes

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However, its important to note that these potential benefits are still being explored, and more studies are needed before we can say for sure how semaglutide impacts fatigue in fibromyalgia

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