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Endogenous causes (medical conditions) When B12 is elevated without supplementation , it can indicate that the body is releasing stored B12 from damaged tissues, producing excess B12-binding proteins, or failing to clear B12 normally

Hippocampus Regarding catalase activity (Fig

The peptide also stabilises nitric oxide synthase activity, reducing oxidative stress that compounds inflammatory damage

Free Radic Biol Med (2018) 127:1604

Occasionally large proliferative hepatocellular lesions are observed that are difficult to diagnose

Continual treatment throughout life is vital, as loss of biochemical control in later stages can lead to severe complications