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Clinical trials of GLP-1 medications, including the STEP program for semaglutide and SURMOUNT trials for tirzepatide, have documented improvements in physical function scores and quality of life measures
Whilst the early evidence for retatrutide liver fat reduction is scientifically promising, patients are best served by working within established NHS pathways and awaiting the outcome of robust Phase 3 trial data and formal regulatory review before drawing firm conclusions about this emerging therapy
Table 2 Summary of the main studies with GLP1-AR
How Retatrutide Works This investigational therapy is designed to mimic three naturally occurring hormones that play key roles in hunger regulation and metabolism
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