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The authors also thank the Michigan Regional Comprehensive Metabolomics Core for their assistance with the metabolomic analysis and interpretation of the data

There were no changes in training or dietary protocols other than the administration of glutathione intravenously

Cysteine is the most important building block because it contains the sulfur needed for detoxification

Free glutathione cannot reach this depth

Potentiation of treosulfan toxicity by the glutathione-depleting agent buthionine sulfoximine in human malignant glioma cells: the role of bcl-2